Despite a long history of successful, community-led harm reduction programs and rising health inequalities suffered by PWUD, research collaborations between PWUD and researchers remain generally ignored. PWUDs are crucial in identifying developing concerns in the drug industry, as well as related health behaviors and consequences. PWUD are thus ideally positioned to contribute meaningfully to all parts of the research process, including the generation of research questions, the conceptualization of study design, and the contextualization of findings.

It is suggested that PWUD have unrivaled...

Abstract
Introduction: Polysubstance use is a prevalent substance use pattern with adverse effects on psychological distress and diminished treatment outcomes. Although polysubstance use often dominates clinical practice, the trajectories of substance use and psychological distress in the initial phase of treatment have been subject to few empirical investigations.

Material and Methods: 141 patients initiating inpatient or outpatient treatment for substance use disorder were followed for 12 months, using multiple assessments. We assessed psychological distress and substance use at baseline...