ABSTRACT: Kratom (Mitragyna speciosa), a plant native to Southeast Asia, has gained global popularity due to both its dose-dependent stimulant and sedative effects. This has raised concerns, particularly around adolescent use, as regular consumption can lead to dependence and withdrawal symptoms. In the Czech Republic, kratom is reportedly used alongside cannabis among adolescents. However, there is limited clinical data on the impact of kratom dependence within this demographic. This study aims to address this gap by exploring adolescent kratom use from the clinical and healthcare policy...