Source: Wakeman SE, Larochelle MR, Ameli O, et al. Comparative Effectiveness of Different Treatment Pathways for Opioid Use Disorder. JAMA Netw Open. 2020;3(2):e1920622. doi:10.1001/jamanetworkopen.2019.20622 Key Points Question What is the real-world effectiveness of different treatment pathways...
Source: Huhn AS, Hobelmann JG, Strickland JC, et al. Differences in Availability and Use of Medications for Opioid Use Disorder in Residential Treatment Settings in the United States. JAMA Netw Open. 2020;3(2):e1920843. doi:10.1001/jamanetworkopen.2019.20843 Key Points Question Do residential...
Source: Ahamad, K., Dong, H., Johnson, C. et al. Factors associated with willingness to wear an electronic overdose detection device. Addict Sci Clin Pract 14, 23 (2019). https://doi.org/10.1186/s13722-019-0153-5 Abstract Background North America is in the midst of an opioid overdose epidemic...
Source: Gangal NS, Hincapie AL, Jandarov R, et al. Association Between a State Law Allowing Pharmacists to Dispense Naloxone Without a Prescription and Naloxone Dispensing Rates. JAMA Netw Open. 2020;3(1):e1920310. doi:10.1001/jamanetworkopen.2019.20310 Key Points Question Is an Ohio law allowing...
Source: National Academies of Sciences, Engineering, and Medicine. 2020. Opportunities to Improve Opioid Use Disorder and Infectious Disease Services: Integrating Responses to a Dual Epidemic. Washington, DC: The National Academies Press. https://doi.org/10.17226/25626. Opioid use and infectious...
Source: Warrington et al. Addict Sci Clin Pract (2020) 15:3 https://doi.org/10.1186/s13722-020-0178-9 Abstract Background Urine drug monitoring for medications for opioid use disorder (MOUD) such as buprenorphine can help to support treatment adherence. The practice of introducing unconsumed...
Source: Pytell, J.D., Buresh, M.E. & Graddy, R. Outcomes of a novel office-based opioid treatment program in an internal medicine resident continuity practice. Addict Sci Clin Pract 14, 46 (2019) doi:10.1186/s13722-019-0175-z Abstract Background The integration of opioid use disorder (OUD) care and...
Source: Darpö, B., Pirner, M., Longstreth, J., & Ferber, G. (2019). Effect of lofexidine on cardiac repolarization during treatment of opioid withdrawal. Drug and alcohol dependence, 205, 107596. Highlights Small mean QTcF increases were observed with lofexidine (<8 ms) on Days 1–2. QTcF mean...
Source: Dietze P, Jauncey M, Salmon A, et al. Effect of Intranasal vs Intramuscular Naloxone on Opioid Overdose: A Randomized Clinical Trial. JAMA Netw Open. 2019;2(11):e1914977. doi:https://doi.org/10.1001/jamanetworkopen.2019.14977 Key Points Question Is 800 μg of naloxone hydrochloride...
Source: CMAJ Open 2019. DOI:10.9778/cmajo.20190026 Abstract Background: Rates of cannabis use among patients receiving methadone maintenance therapy are high, and cannabis use may be associated with outcomes of methadone maintenance therapy. We examined the effect of cannabis use on opioid use in...
Source: Dietze P, Jauncey M, Salmon A, et al. Effect of Intranasal vs Intramuscular Naloxone on Opioid Overdose: A Randomized Clinical Trial. JAMA Netw Open. 2019;2(11):e1914977. doi:https://doi.org/10.1001/jamanetworkopen.2019.14977 Key Points Question Is 800 μg of naloxone hydrochloride...
NDEWS Coordinating Center Air date: October 29, 2019 Lee Hoffer, Ph.D. Department of Anthropology Case Western Reserve Cleveland OH Kavita Babu, M.D. Division of Medical Toxicology Department of Emergency Medicine University of Massachusetts Medical School Worcester MA Annabelle Belcher, Ph.D...
Source: Hall, O. T., Hall, O. E., McGrath, R. P., & Haile, Z. T. (2019). Years of Life Lost due to Opioid Overdose in Ohio: Temporal and Geographic Patterns of Excess Mortality. Journal of addiction medicine. Abstract Objectives: The aim of the study was to quantify the burden of premature mortality...
The Substance Abuse and Mental Health Services Administration (SAMHSA)
The success of treatment and recovery of individuals with opioid use disorder (OUD) can vary. Most often, a combination of factors adds complexities to evaluating the effectiveness of services and interventions.
Worldwide, overdose is the leading cause of avoidable death among people who inject drugs. An important area of concern for the Substance Abuse and Mental Health Services Administration (SAMHSA) is promoting policies and practices to lower the risk of overdose for persons with opioid use disorder who are, or have been, in contact with criminal justice systems.
Daliah Heller, Vital Strategies’ Director of Drug Use Initiatives, moderates a discussion between Tracie Gardner, Legal Action Center’s Vice President of Policy Advocacy, and Dr. Chinazo Cunningham, Professor of Medicine and Associate Chief of the Division of General Internal Medicine at Albert...
Source: Zhong, B. L., Xu, Y. M., Xie, W. X., Lu, J., Yu, W. B., & Yan, J. (2019). Alcohol drinking in Chinese methadone-maintained clients: a self-medication for depression and anxiety?. Journal of addiction medicine, 13(4), 314-321. Abstract Objectives: Unhealthy alcohol use is associated with...
Source: Bedene A, Lijfering WM, Niesters M, et al. Opioid Prescription Patterns and Risk Factors Associated With Opioid Use in the Netherlands. JAMA Netw Open. Published online August 28, 20192(8):e1910223. doi:10.1001/jamanetworkopen.2019.10223 KEY POINTS Question Are the prevalence of opioid...
