Legal and illegal psychoactive compounds that alter brain function, leading to changes in perception, mood, consciousness, and behaviour.
Psychoactive Substances
Supporting the Journey: A Reading List for Addiction Nurses
As we celebrate International Nurses Week, we honour the dedication, expertise, and compassion of nurses around the globe—especially those working on the frontlines of substance use prevention, treatment, and recovery support. Addiction...
Substance Use Disorders: A Guide for the Primary Care Provider
This practical and up-to-date guide offers comprehensive support for primary care clinicians managing patients with substance use disorders. Covering a wide range of substances and clinical scenarios, the book is organized into four parts...
The role of UK alcohol and drug (AOD) nurses in a changing workforce
Background: This article shares findings from a study that looked into how alcohol and other drugs (AOD) nurses in the UK view their current career opportunities and the challenges they face. It also explores how changes in health services...
National Training Program on Prevention in Schools: The Paraguayan Experience
EXECUTIVE SUMMARY In 2024, a public call from the Ministry of Education and Science for the contracting of a higher education institution to design and implement a training programme in strategies for preventing psychoactive substance use...
Barriers and facilitators to scaling up medications for opioid use disorder in Kentucky: qualitative perspectives of treatment organisation staff
Background Many people who could benefit from medications for opioid use disorder (MOUD) aren’t receiving them. This study looks at how MOUD agencies in Kentucky are experiencing changes in patient numbers and the challenges and supports...
Canadian Substance Use Costs and Harms Online Data Visualisation Tool
CSUCH’s data visualisation tool can be used to estimate substance use trends across the country. The data helps inform programs, practices, and research to protect communities, save lives, and improve the well-being of people in Canada...

Perceived impacts of North Americas first de-medicalised safer supply program
Background A non-medicalized safer supply model called a “Compassion Club” has recently been evaluated. The model involved providing rigorously tested and accurately labeled illicit substances to members at cost. Operating for 14 months in...
VCU researchers are developing a long-acting medication for opioid addiction
Researchers at Virginia Commonwealth University (VCU) have developed a new version of a medication for opioid use disorder that could offer longer-lasting treatment. Current medications for opioid addiction often require daily doses, but...
The changing DNA of serious and organised crime
Europol’s EU Serious and Organised Crime Threat Assessment (EU-SOCTA) 2025, published today, reveals how the very DNA of crime is shifting – reshaping the tactics, tools and structures employed by criminal networks. The EU-SOCTA offers one...

Substance Use Monitoring and Surveillance: Challenges faced by LMICs
Substance use surveillance has emerged as a crucial public health strategy across Africa, particularly in light of the alarming rise in substance use among adolescents (1). This trend poses significant health risks that require a...
