Source: Busquets-Garcia, A., Bains, J. & Marsicano, G. CB1 Receptor Signaling in the Brain: Extracting Specificity from Ubiquity. Neuropsychopharmacol. 43, 4–20 (2018). https://doi.org/10.1038/npp.2017.206 Abstract Endocannabinoids (eCBs) are amongst the most ubiquitous signaling molecules in the...

Source: Li, G., Chihuri, S. Is marijuana use associated with decreased use of prescription opioids? Toxicological findings from two US national samples of drivers. Subst Abuse Treat Prev Policy 15, 12 (2020). https://doi.org/10.1186/s13011-020-00257-7 Abstract Background State governments in the...

Source: Montgomery, S., Sirju, K., Bear, J. et al. Recurrent priapism in the setting of cannabis use. J Cannabis Res 2, 7 (2020). https://doi.org/10.1186/s42238-020-0015-8 Abstract Priapism (persistent and painful erection of the penis) is a notable urological emergency, with over 90% of those...

Source: Martínez Mota, L., Jiménez Rubio, G., Hernández Hernández, O. T., & Páez Martínez, N. (2018). Influence of the type of childhood violence on cannabis abuse and dependence among adolescents: a systematic review and meta-analysis. Adicciones, 1050-1050. http://dx.doi.org/10.20882/adicciones...

Source: Citti, C., Linciano, P., Russo, F. et al. A novel phytocannabinoid isolated from Cannabis sativa L. with an in vivo cannabimimetic activity higher than Δ9-tetrahydrocannabinol: Δ9-Tetrahydrocannabiphorol. Sci Rep 9, 20335 (2019). https://doi.org/10.1038/s41598-019-56785-1 Abstract (-)-Trans...

Source: Dahlgren, M. K., Sagar, K. A., Smith, R. T., Lambros, A. M., Kuppe, M. K., & Gruber, S. A. (2020). Recreational cannabis use impairs driving performance in the absence of acute intoxication. Drug and Alcohol Dependence, 107771. Highlights •Cannabis users had poorer driving simulator...

Source: Pratt, M., Stevens, A., Thuku, M. et al. Benefits and harms of medical cannabis: a scoping review of systematic reviews. Syst Rev 8, 320 (2019) doi:10.1186/s13643-019-1243-x Abstract Background There has been increased interest in the role of cannabis for treating medical conditions. The...

Source: Shanahan M, Ritter A (2014) Cost Benefit Analysis of Two Policy Options for Cannabis: Status Quo and Legalisation. PLoS ONE 9(4): e95569. https://doi.org/10.1371/journal.pone.0095569 Abstract Aims To date there has been limited analysis of the economic costs and benefits associated with...

Source: Ghasemiesfe M, Barrow B, Leonard S, Keyhani S, Korenstein D. Association Between Marijuana Use and Risk of Cancer: A Systematic Review and Meta-analysis. JAMA Netw Open. 2019;2(11):e1916318. doi:https://doi.org/10.1001/jamanetworkopen.2019.16318 Key Points Question What is the association...

Source: Madras BK, Han B, Compton WM, Jones CM, Lopez EI, McCance-Katz EF. Associations of Parental Marijuana Use With Offspring Marijuana, Tobacco, and Alcohol Use and Opioid Misuse. JAMA Netw Open.2019;2(11):e1916015. doi:https://doi.org/10.1001/jamanetworkopen.2019.16015 Key Points Question Is...

Source: CMAJ Open 2019. DOI:10.9778/cmajo.20190026 Abstract Background: Rates of cannabis use among patients receiving methadone maintenance therapy are high, and cannabis use may be associated with outcomes of methadone maintenance therapy. We examined the effect of cannabis use on opioid use in...

Source: Freeman, T. P., & Winstock, A. R. (2015). Examining the profile of high-potency cannabis and its association with severity of cannabis dependence. Psychological medicine, 45(15), 3181-3189. Abstract Background Cannabis use is decreasing in England and Wales, while demand for cannabis...

Source: Shollenbarger S, Thomas AM, Wade NE, Gruber SA, Tapert SF, Filbey FM and Lisdahl KM (2019). Intrinsic Frontolimbic Connectivity and Mood Symptoms in Young Adult Cannabis Users. Front. Public Health 7:311. doi: 10.3389/fpubh.2019.00311 Objective: The endocannbinoid system and cannabis...

Source: Smyth, B. P., O’Farrell, A., & Daly, A. (2019). Cannabis use and Associated Health Problems–What’s the Harm?. Irish medical journal, 112(9), 1000-1000. Abstract Aim Cannabis is the most widely used illegal drug in Ireland. We sought to describe the changing pattern of cannabis use and...

Source: Leas EC, Nobles AL, Caputi TL, Dredze M, Smith DM, Ayers JW. Trends in Internet Searches for Cannabidiol (CBD) in the United States. JAMA Netw Open. Published online October 23, 20192(10):e1913853. doi:10.1001/jamanetworkopen.2019.13853 Introduction Cannabidiol (CBD) is widely promoted as a...

Source: Dai H, Richter KP. A National Survey of Marijuana Use Among US Adults With Medical Conditions, 2016-2017. JAMA Netw Open. Published online September 20, 20192(9):e1911936. doi:10.1001/jamanetworkopen.2019.11936 Key Points Question What are the prevalence and patterns of marijuana use among...

Source: Bloomfield, M. A., Hindocha, C., Green, S. F., Wall, M. B., Lees, R., Petrilli, K., ... & Freeman, T. P. (2018). The neuropsychopharmacology of cannabis: a review of human imaging studies. Pharmacology & therapeutics. Abstract The laws governing cannabis are evolving worldwide and associated...

Source: van Draanen et al. Substance Abuse Treatment, Prevention, and Policy (2019) 14:38 https://doi.org/10.1186/s13011-019-0224-3 Abstract Background: Public health and governmental organizations are expected to provide guidance to the public on emerging health issues in accessible formats. It is...

Source: https://www.who.int/medicines/access/controlled-substances/Section4.CannabisPlant.TherapeuticUse.pdf?ua=1 Extent of therapeutic use and epidemiology of medical use It is estimated that between 3% and 5% of the world’s population has tried cannabis for nonmedical reasons. Among users of...

Source: : Rehm J, Crépault JF, Fischer B. The devil is in the details! On regulating cannabis use in Canada based on public health criteria: Comment on “Legalizing and regulating marijuana in Canada: review of potential economic, social, and health impacts.” Int J Health Policy Manag. 2017;6(3):173...